2018

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  1. Andrs, Martin; Pospíšilová, Monika; Seifrtová, Martina; Havelek, Radim; Tichy, Ales; Vejrychová, Kateřina; Poledníková, Michaela; Górecki, Lukáš; Jun, Daniel; Korábečný, Jan; Řezáčová, Martina: Purin-6-one and pyrrolo[2,3-d]pyrimidin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity. In: Future Medicinal Chemistry, 2018, roč. 10, č. 17. s. 2029-2038. IF 3.969.
  2. Arshad, Maria; Fatmi, Muhammad Qaiser; Musílek, Kamil; Hussain, Alamdar; Kuča, Kamil; Petroianu, Georg; Kalasz, Huba; Nurulain, Syed Muhammad: In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication. In: Toxicology Mechanisms and Methods, 2018, roč. 28, č. 1. s. 62-68. IF 1.994.
  3. Benek, Ondřej; Hroch, Lukáš; Aitken, Laura; Gunn-Moore, Frank; Vinklářová, Lucie; Kuča, Kamil; Perez, Daniel I.; Perez, Concepcion; Martinez, Ana; Fišar, Zdeněk; Musílek, Kamil: 1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders. In: Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, roč. 33, č. 1. s. 665-670. IF 3.638.
  4. de Souza, Felipe Rodrigues; Garcia, Danielle Rodrigues; Cuya, Teobaldo; Kuča, Kamil; de Alencastro, Ricardo Bicca; Costa Franca, Tanos Celmar: Behavior of uncharged oximes compared to HI6 and 2-PAM in the human AChE-tabun conjugate: a molecular modeling approach. In: Journal of Biomolecular Structure and Dynamics, 2018, roč. 36, č. 6. s. 1430-1438. IF 3.107.
  5. Doležal, Rafael; Karásková, Natálie; Musil, Karel; Novák, Martin; Maltsevskaya, Nadezhda V.; Maliňák, Dávid; Kolář, Karel; Soukup, Ondřej; Kuča, Kamil; Žďárová Karasová, Jana: Characterization of the penetration of the blood-brain barrier by high-performance liquid chromatography (HPLC) using a stationary phase with an immobilized artificial membrane. In: Analytical Letters, 2018, roč. 51, č. 15. s. 2401-2414. IF 1.206.
  6. Durisova, Kamila; Cechakova, Lucie; Jošt, Petr; Sinkorova, Zuzana; Kmochova, Adela; Pejchal, Jaroslav; Ondrej, Martin; Vavrova, Jirina; Tichý, Aleš: DNA repair inhibitors as radiosensitizers in human lung cells. In: Journal of Applied Biomedicine, 2018, roč. 16, č. 1. s. 66-74. IF 1.783.
  7. Hepnarová, Vendula; Korábečný, Jan; Matoušková, Lenka; Jošt, Petr; Mučková, Lubica; Hrabinová, Martina; Vykoukalová, Nikol; Kerhartová, Markéta; Kucera, Tomáš; Doležal, Rafael; Nepovimová, Eugenie; Špilovská, Katarína; Mezeiová, Eva; Pham, Ngoc Lam; Jun, Daniel; Štaud, František; Kaping, D.; Kuča, Kamil; Soukup, Ondřej: The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease. In: European Journal of Medicinal Chemistry, 2018, roč. 150, č. April. s. 292-306. IF 4.816.
  8. Honegr, Jan; Doležal, Rafael; Maliňák, Dávid; Benková, Markéta; Soukup, Ondřej; de Almeida, Joyce S.F.D.; Franca, Tanos C. C.; Kuča, Kamil; Prymula, Roman: Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery. In: Molecules, 2018, roč. 23, č. 1. s. nestránkováno. IF 3.098.
  9. Honegr, Jan; Maliňák, Dávid; Doležal, Rafael; Soukup, Ondřej; Benková, Markéta; Hroch, Lukáš; Benek, Ondřej; Janočková, Jana; Kuča, Kamil; Prymula, Roman: Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro. In: European Journal of Medicinal Chemistry, 2018, roč. 146, č. February. s. 38-46. IF 4.816.
  10. Hrabinová, Martina; Misík, Jan; Jun, Daniel; Kuča, Kamil: Reactivation potential of novel more lipophilic pralidoxime analogs. In: Letters in Drug Design & Discovery, 2018, roč. 15, č. 8. s. 822-827. IF 0.924.
  11. Chioua, Mourad; Serrano, Estefania; Dgachi, Youssef; Martin, Helene; Jun, Daniel; Janočková, Jana; Sepsova, Vendula; Soukup, Ondřej; Moraleda, Ignacio; Chabchoub, Fakher; Ismaili, Lhassane; Iriepa, Isabel; Marco-Contelles, Jose: Synthesis, Biological Assessment and Molecular Modeling of Racemic QuinoPyranoTacrines for Alzheimer's Disease Therapy. In: ChemistrySelect [online], 2018, roč. 3, č. 2. s. 461-466. IF 1.505.
  12. Jacevic, Vesna; Kuča, Kamil; Milovanovic, Zoran; Bocarov-Stancic, Aleksandra; Rancic, Ilija; Bokonjic, Dubravko; Dragojevic-Simic, Viktorija; Segrt, Zoran: Gastroprotective effects of amifostine in rats treated by T-2 toxin. In: Toxin Reviews, 2018, roč. 37, č. 2. s. 123-127. IF 1.887.
  13. Kaniakova, Martina; Kleteckova, Lenka; Lichnerova, Katarina; Holubova, Kristina; Skrenkova, Kristina; Korinek, Miloslav; Krusek, Jan; Smejkalova, Tereza; Korábečný, Jan; Vales, Karel; Soukup, Ondřej; Horak, Martin: 7-Methoxyderivative of tacrine is a 'foot-in-the-door' open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo. In: Neuropharmacology, 2018, roč. 140, č. September. s. 217-232. IF 4.249.
  14. Klímová, Blanka; Novotný, Michal; Kuča, Kamil: Semantic Dementia: A Mini-Review. In: Mini-Reviews in Medicinal Chemistry, 2018, roč. 18, č. 1. s. 3-8. IF 2.645.
  15. Klímová, Blanka; Novotný, Michal; Kuča, Kamil: Anti-Aging Drugs - Prospect of Longer Life?. In: Current Medicinal Chemistry, 2018, roč. 25, č. 17. s. 1946-1953. IF 3.469.
  16. Klímová, Blanka; Marešová, Petra; Novotný, Michal; Kuča, Kamil: A Global View on Narcolepsy - A Review Study. In: Mini-Reviews in Medicinal Chemistry, 2018, roč. 18, č. 5. s. 458-464. IF 2.645.
  17. Klímová, Blanka; Vališ, Martin; Talábová, Marika; Kuchyňka, Jiří; Kuča, Kamil: Pediatric Narcolepsy: A Brief Report. In: Clinical Pediatrics, 2018, roč. 57, č. 6. s. 738-740. IF 1.409.
  18. Konkol'ová, Eva; Janočková, Jana; Perjési, Pál; Vašková, Janka; Kožurková, Mária: Selected ferrocenyl chalcones as DNA/BSA-interacting agents and inhibitors of DNA topoisomerase I and II activity. In: Journal of Organometallic Chemistry, 2018, roč. 861, č. April. s. 1-9. IF 1.946.
  19. Korábečný, Jan; Nepovimová, Eugenie; Cikánková, Tereza; Špilovská, Katarína; Vašková, Lucie; Mezeiová, Eva; Kuča, Kamil; Hroudová, Jana: Newly developed drugs for Alzheimer's disease in relation to energy metabolism, cholinergic and monoaminergic neurotransmission. In: Neuroscience, 2018, roč. 370, č. February. s. 191-206. IF 3.382.
  20. Korábečný, Jan: Prokognitivní potenciál bis(7)-takrinu jako zvažovaného terapeutika neurodegenerativních onemocnění. In: Vojenské zdravotnické listy, 2018, roč. 87, č. 1. s. 34-44.
  21. Krajňáková, Lucia; Pisarčiková, Jana; Drajna, Ladislav; Labudová, Martina; Imrich, Ján; Paulíková, Helena; Kožurková, Mária: Intracellular distribution of new tacrine analogues as a potential cause of their cytotoxicity against human neuroblastoma cells SH-SY5Y. In: Medicinal Chemistry Research, 2018, roč. 27, č. 10. s. 2353-2365. IF 1.607.
  22. Kuca, Kamil; Musílek, Kamil; Jun, Daniel; Pejchal, Jaroslav; Krejcar, Ondrej; Penhaker, Marek; Wu, Qinghua; Lopes, Raquel O.; Ramalho, Teodorico C.; Franca, Tanos C. C.; Nepovimova, Eugenie; Soukup, Ondřej: Oxime K033-reactivation Activity of Cholinesterases Inhibited by Various Nerve Agents and Organophosphorus Pesticides. In: Letters in Drug Design & Discovery, 2018, roč. 15, č. 11. s. 1124-1130. IF 0.924.
  23. Kuča, Kamil; Jun, Daniel; Junová, Lucie; Musílek, Kamil; Hrabinová, Martina; Valle da Silva, Jorge Alberto; Ramalho, Teodorico Castro; Valko, Marian; Wu, Qinghua; Nepovímová, Eugenie; Costa Franca, Tanos Celmar: Synthesis, biological evaluation, and docking studies of novel bisquaternary aldoxime reactivators on Acetylcholinesterase and Butyrylcholinesterase inhibited by paraoxon. In: Molecules, 2018, roč. 23, č. 5. s. nestránkováno. IF 3.098.
  24. Kuča, Kamil; Musílek, Kamil; Jun, Daniel; Žďárová Karasová, Jana; Nepovimová, Eugenie; Soukup, Ondřej; Hrabinová, Martina; Mikler, John; Franca, Tanos C. C.; Da Cunha, Elaine F. F.; De Castro, Alexandre A.; Vališ, Martin; Ramalho, Teodorico: A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase. In: BMC pharmacology & toxicology, 2018, roč. 19, č. February. s. nestránkováno. IF 1.865.
  25. Kuča, Kamil; Žďárová Karasová, Jana; Soukup, Ondřej; Kassa, Jiří; Novotná, Eva; Šepsová, Vendula; Horová, Anna; Pejchal, Jaroslav; Hrabinová, Martina; Vodáková, Eva; Jun, Daniel; Nepovimová, Eugenie; Vališ, Martin; Musílek, Kamil: Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings. In: Drug Design, Development and Therapy, 2018, roč. 12, č. March. s. 505-512. IF 2.935.
  26. Lenčo, Juraj; Vajrychová, Marie; Pimková, Kristýna; Prokšová, Magdaléna; Benková, Markéta; Klimentová, Jana; Tambor, Vojtěch; Soukup, Ondřej: Conventional-Flow Liquid Chromatography-Mass Spectrometry for Exploratory Bottom-Up Proteomic Analyses. In: Analytical Chemistry, 2018, roč. 90, č. 8. s. 5381-5389. IF 6.042.
  27. Lizewska, Barbara; Teul, Joanna; Kuc, Pawel; Lemancewicz, Adam; Charkiewicz, Karol; Goscik, Joanna; Kacerovský, Marian; Menon, Ramkumar; Miltyk, Wojciech; Laudanski, Piotr: Maternal Plasma Metabolomic Profiles in Spontaneous Preterm Birth: Preliminary Results. In: Mediators of Inflammation, 2018, roč. Neuveden, č. 2018. s. nestránkováno. IF 3.549.
  28. Maliňák, Dávid; Korábečný, Jan; Soukup, Ondřej; Górecki, Lukáš; Nepovimová, Eugenie; Psotka, Miroslav; Doležal, Rafael; Nguyen, Thuy Duong; Mezeiová, Eva; Musílek, Kamil; Kuča, Kamil: A review of the synthesis of quaternary Acetylcholinesterase reactivators. In: Current Organic Chemistry, 2018, roč. 22, č. 16. s. 1619-1648. IF 2.193.
  29. Marek, Jan; Josková, Věra; Doležal, Rafael; Soukup, Ondřej; Benková, Markéta; Fučíková, Alena; Maliňák, Dávid; Boštíková, Vanda; Kuča, Kamil: Synthesis, antimicrobial effect and surface properties of hydroxymethyl-substituted pyridinium salts. In: Letters in Drug Design & Discovery, 2018, roč. 15, č. 8. s. 828-842. IF 0.924.
  30. Marek, Jan; Maliňák, Dávid; Doležal, Rafael; Soukup, Ondřej; Benková, Markéta; Nachtigal, Petr; Vavral, Petr; Kuča, Kamil: Novel Series of Quaternary Ammonium Surfactants Based on 2,3-Dihydro-[1,4]dioxino[2.3-b]pyridin-7-ol Ring: Synthesis, Analysis and Antimicrobial Evaluation. In: Letters in Organic Chemistry, 2018, roč. 15, č. 1. s. 3-9. IF 0.539.
  31. Mezeiová, Eva; Špilovská, Katarína; Nepovimová, Eugenie; Górecki, Lukáš; Soukup, Ondřej; Doležal, Rafael; Maliňák, Dávid; Janočková, Jana; Jun, Daniel; Kuča, Kamil; Korábečný, Jan: Profiling donepezil template into multipotent hybrids with antioxidant properties. In: Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, roč. 33, č. 1. s. 583-606. IF 3.638.
  32. Misík, Jan; Nepovimová, Eugenie; Pejchal, Jaroslav; Kassa, Jiri; Korábečný, Jan; Soukup, Ondřej: Cholinesterase Inhibitor 6-Chlorotacrine - In Vivo Toxicological Profile and Behavioural Effects. In: Current Alzheimer Research, 2018, roč. 15, č. 6. s. 552-560. IF 3.289.
  33. Navrátilová, Zdeňka; Patočka, Jiří: Mucuna pruriens: antiparkinsonikum rostlinného původu. In: Psychiatrie, 2018, roč. 22, č. 1. s. 28-32.
  34. Novotný, Michal; Vališ, Martin; Klímová, Blanka: Tourette Syndrome: A Mini-Review. In: Frontiers in Neurology, 2018, roč. 9, č. neuvedeno. s. nestránkováno. IF 3.508.
  35. Othman, Salem; Kožurková, Mária: Sulfur containing acridin derivatives in preclinical studies with cancer cell lines. In: Current Medicinal Chemistry, 2018, roč. 25, č. 17. s. 1968-1975. IF 3.469.
  36. Panek, Dawid; Wieckowska, Anna; Jonczyk, Jakub; Godyn, Justyna; Bajda, Marek; Wichur, Tomasz; Pasieka, Anna; Knez, Damijan; Pislar, Anja; Korábečný, Jan; Soukup, Ondřej; Šepsová, Vendula; Sabate, Raimon; Kos, Janko; Gobec, Stanislav; Malawska, Barbara: Design, synthesis, and biological evaluation of 1-benzylamino-2-hydroxyalkyl derivatives as new potential disease-modifying multifunctional anti-Alzheimer's agents. In: ACS Chemical Neuroscience, 2018, roč. 9, č. 5. s. 1074-1094. IF 4.211.
  37. Patočka, Jiří; Navrátilová, Zdeňka: Celastrus Paniculatus: rostlinné nootropikum. In: Psychiatrie, 2018, roč. 22, č. 2. s. 83-86.
  38. Patočka, Jiří: Novichok agents - mysterious poisonous substances from the cold war period. In: Vojenské zdravotnické listy, 2018, roč. 87, č. 2. s. 92-94.
  39. Patočka, Jiří: Bolesatine, a toxic protein from the mushroom Rubroboletus satanas. In: Vojenské zdravotnické listy, 2018, roč. 87, č. 1. s. 14-20.
  40. Patočka, Jiří; Nepovimová, Eugenie; Wu, Quinghua; Kuča, Kamil: Palytoxin congeners. In: Archives of Toxicology, 2018, roč. 92, č. 1. s. 143-156. IF 5.728.
  41. Pavlíková, Růžena; Misík, Jan; Cabal, Jiří; Marek, Jan; Kuča, Kamil: In vitro skin decontamination of paraoxon - wet-type cleansing effect of selected detergents. In: Cutaneous and Ocular Toxicology, 2018, roč. 37, č. 1. s. 77-83. IF 0.888.
  42. Port, M.; Majewski, M.; Herodin, F.; Valente, M.; Drouet, M.; Forcheron, F.; Tichý, Aleš; Sirák, Igor; Zavřelová, Alžběta; Málková, Andrea; Becker, B. V.; Veit, D. A.; Waldeck, S.; Badie, C.; O'Brien, G.; Christiansen, H.; Wichmann, J.; Eder, M.; Beutel, G.; Vachelova, J.; Doucha-Senf, S.; Abend, M.: Validating baboon Ex Vivo and In Vivo radiation-related gene expression with corresponding human data. In: Radiation Research, 2018, roč. 189, č. 4. s. 389-398. IF 2.530.
  43. Radochová, Vladimíra; Kacerovská Musilová, Ivana; Štěpán, Martin; Veščičík, Peter; Slezák, Radovan; Jasobsson, Bo; Kacerovský, Marian: Periodontal disease and intra-amniotic complications in women with preterm prelabor rupture of membranes. In: The Journal of Maternal-Fetal & Neonatal Medicine, 2018, roč. 31, č. 21. s. 2852-2861. IF 1.493.
  44. Richterová, Martina; Štětina, Rudolf; Jošt, Petr; Svobodová, Hana; Řeháček, Vít; Kassa, Jiří: Inter strand crosslinks in DNA induced in vivo by percutaneous application of sulphur mustard to rats and mice. In: Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2018, roč. 832, č. August. s. 35-40. IF 1.996.
  45. Sabolová, Danica; Kristian, Pavol; Kožurková, Mária: Multifunctional properties of novel tacrine congeners: cholinesterase inhibition and cytotoxic activity. In: Journal of Applied Toxicology, 2018, roč. 38, č. 11. s. 1377-1387. IF 2.909.
  46. Schmidt, Monika; Hrabcová, Veronika; Jun, Daniel; Kuča, Kamil; Musílek, Kamil: Vector Control and Insecticidal Resistance in the African Malaria Mosquito Anopheles gambiae. In: Chemical Research in Toxicology, 2018, roč. 31, č. 7. s. 534-547. IF 3.432.
  47. Soukup, Ondřej; Korábečný, Jan; Maliňák, Dávid; Nepovimová, Eugenie; Pham, Ngoc L.; Musílek, Kamil; Hrabinová, Martina; Hepnarová, Vendula; Doležal, Rafael; Pávek, Petr; Jost, Petr; Kobrlová, Tereza; Janočková, Jana; Górecki, Lukáš; Psotka, Miroslav; Nguyen, Thuy Duong; Box, Karl; Outhwaite, Breeze; Čečková, Martina; Šorf, Aleš; Jun, Daniel; Kuča, Kamil: In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?. In: Medicinal Chemistry, 2018, roč. 14, č. 3. s. 281-292. IF 2.631.
  48. Tichý, Aleš; Kabacik, Sylwia; O'Brien, Grainne; Pejchal, Jaroslav; Sinkorova, Zuzana; Kmochova, Adela; Sirák, Igor; Málková, Andrea; Beltran, Caterina Gomila; Gonzalez, Juan Ramon; Grepl, Jakub; Majewski, Matthaeus; Ainsbury, Elizabeth; Zárybnická, Lenka; Vachelová, Jana; Zavřelová, Alžběta; Davidkova, Marie; Šťastná-Marková, Markéta; Abend, Michael; Pernot, Eileen; Cardis, Elisabeth; Badie, Christophe: The first in vivo multiparametric comparison of different radiation exposure biomarkers in human blood. In: PLoS One, 2018, roč. 13, č. 2. s. nestránkováno. IF 2.766.
  49. Wieckowska, Anna; Wichur, Tomasz; Godyn, Justyna; Bucki, Adam; Marcinkowska, Monika; Siwek, Agata; Wieckowski, Krzysztof; Zareba, Paula; Knez, Damijan; Gluch-Lutwin, Monika; Kazek, Grzegorz; Latacz, Gniewomir; Mika, Kamil; Kolaczkowski, Marcin; Korábečný, Jan; Soukup, Ondřej; Benková, Markéta; Kiec-Kononowicz, Katarzyna; Gobec, Stanislav; Malawska, Barbara: Novel multitarget-directed ligands aiming at symptoms and causes of Alzheimer's disease. In: ACS Chemical Neuroscience, 2018, roč. 9, č. 5. s. 1195-1214. IF 4.211.
  50. Žárská, Monika; Sramek, Michal; Novotný, Filip; Havel, Filip; Babelova, Andrea; Mrazkova, Hanka; Benada, Oldřich; Reinis, Milan; Stepanek, Ivan; Musílek, Kamil; Bartek, Jiří; Ursinyova, Monika; Novák, Ondřej; Dzijak, Rastislav; Kuča, Kamil; Proška, Jan; Hodný, Zdeněk: Biological safety and tissue distribution of (16-mercaptohexadecyl) trimethylammonium bromide-modified cationic gold nanorods. In: Biomaterials, 2018, roč. 154, č. February. s. 275-290. IF 8.806.
  51. Žďárová Karasová, Jana; Mžik, Martin; Hroch, Miloš; Korábečný, Jan; Nepovimová, Eugenie; Voříšek, Viktor; Palička, Vladimír; Kuča, Kamil: The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats. In: Basic & Clinical Pharmacology & Toxicology, 2018, roč. 122, č. 4. s. 373-382. IF 2.659.
  52. Žďárová Karasová, Jana; Šesták, Vít; Korábečný, Jan; Mezeiová, Eva; Palička, Vladimír; Kuča, Kamil; Mžik, Martin: 1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats. In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018, roč. 1092, č. August. s. 350-358. IF 2.441.

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