2020

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  1. BENEK, Ondřej - KORÁBEČNÝ, Jan - SOUKUP, Ondřej. A perspective on multi-target drugs for Alzheimer's disease. Trends in Pharmacological Sciences. 2020, 41(7), 434-445. ISSN 0165-6147. DOI 10.1016/j.tips.2020.04.008.

  2. BUREŠ, Jan - KVĚTINA, Jaroslav - RADOCHOVÁ, Věra - TACHECÍ, Ilja - PETEROVÁ, Eva - HERMAN, David - DOLEŽAL, Rafael - KOPÁČOVÁ, Marcela - REJCHRT, Stanislav - DOUDA, Tomáš - ŠESTÁK, Vít - DOUDA, Ladislav - ŽĎÁROVÁ KARASOVÁ, Jana. The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs. PLoS One. 2020, 15(1), e0227781. ISSN 1932-6203. DOI 10.1371/journal.pone.0227781.

  3. FILIPOVA, Alzbeta - MAREK, Jan - HAVELEK, Radim - PEJCHAL, Jaroslav - JELICOVA, Marcela - CIZKOVA, Jana - MAJOROŠOVÁ, Martina - MUCKOVA, Lubica - KUCERA, Tomas - PRCHAL, Lukáš - PSOTKA, Miroslav - ŽIVNÁ, Natálie - KOUTOVÁ, Darja - SINKOROVA, Zuzana - ŘEZÁČOVÁ, Martina - TICHY, Ales. Substituted piperazines as novel potential radioprotective agents. Molecules. 2020, 25(3), 532. ISSN 1420-3049. DOI 10.3390/molecules25030532.

  4. GÓRECKI, Lukáš - ANDRŠ, Martin - ŘEZÁČOVÁ, Martina - KORÁBEČNÝ, Jan. Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy. Pharmacology & Therapeutics. 2020, 210(Jun), 107518. ISSN 0163-7258. DOI 10.1016/j.pharmthera.2020.107518.

  5. GÓRECKI, Lukáš - ANDRYS, Rudolf - SCHMIDT, Monika - KUCERA, Tomas - PSOTKA, Miroslav - SVOBODOVÁ, Barbora - HRABCOVA, Veronika - HEPNAROVÁ, Vendula - BZONEK, Petr - JUN, Daniel - KUCA, Kamil - KORÁBEČNÝ, Jan - MUSÍLEK, Kamil. Cysteine-Targeted insecticides against A. gambiae Acetylcholinesterase are neither selective nor reversible inhibitors. ACS Medicinal Chemistry Letters. 2020, 11(1), 65-71. ISSN 1948-5875. DOI 10.1021/acsmedchemlett.9b00477.

  6. HONEGR, Jan - JUN, Daniel - KUČA, Kamil - MAREŠOVÁ, Petra. Definition of the target population for external pacemaker as a key aspect in successful medical device HTA process. Military Medical Science Letters - Vojenské zdravotnické listy. 2020, 89(2), 99-107. ISSN 0372-7025. DOI 10.31482/mmsl.2020.003.

  7. HYMPÁNOVÁ, Michaela - KUČERA, Tomáš - BENEK, Ondřej - KORÁBEČNÝ, Jan - MAREK, Jan. Searching for new antimicrobial agents by targeting bacterial nad metabolism: evaluation of frentizole derivatives selected by molecular docking. Military Medical Science Letters - Vojenské zdravotnické listy. 2020, 89(2), 66-73. ISSN 0372-7025. DOI 10.31482/mmsl.2020.005.

  8. KUCA, Kamil - MUSÍLEK, Kamil - JUN, Daniel - NEPOVIMOVA, Eugenie - SOUKUP, Ondřej - KORÁBEČNÝ, Jan - FRANCA, Tanos C. C - DE CASTRO, Alexandre A - KREJCAR, Ondrej - DA CUNHA, Elaine F. F - RAMALHO, Teodorico C. Oxime K074-in vitro and in silico reactivation of acetylcholinesterase inhibited by nerve agents and pesticides. Toxin Reviews. 2020, 39(2), 157-166. ISSN 1556-9543. DOI 10.1080/15569543.2018.1485702.

  9. MALIŇÁK, Dávid - DOLEŽAL, Rafael - HEPNAROVÁ, Vendula - HOZOVÁ, Miroslava - ANDRÝS, Rudolf - BZONEK, Petr - RAČÁKOVÁ, Veronika - KORÁBEČNÝ, Jan - GÓRECKI, Lukáš - MEZEIOVÁ, Eva - PSOTKA, Miroslav - JUN, Daniel - KUČA, Kamil - MUSÍLEK, Kamil. Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators. Journal of Enzyme Inhibition and Medicinal Chemistry. 2020, 35(1), 478-488. ISSN 1475-6366. DOI 10.1080/14756366.2019.1710501.

  10. MAREK, Jan - TICHÝ, Aleš - HAVELEK, Radim - MAJOROŠOVÁ, Martina - FILIPOVÁ, Alžběta - ANDREJSOVÁ, Lenka - KUČERA, Tomáš - PRCHAL, Lukáš - MÚČKOVÁ, Ľubica - ŘEZÁČOVÁ, Martina - ŠINKOROVÁ, Zuzana - PEJCHAL, Jaroslav. A novel class of small molecule inhibitors with radioprotective properties. European Journal of Medicinal Chemistry. 2020, 187(February), UNSP111606. ISSN 0223-5234. DOI 10.1016/j.ejmech.2019.111606.

  11. MARESOVA, Petra - PETER, Lukas - HONEGR, Jan - REZNY, Lukas - PENHAKER, Marek - AUGUSTYNEK, Martin - MOHELSKA, Hana - KLIMOVA, Blanka - KUCA, Kamil. Complexity stage model of the medical device development based on economic evaluation-MedDee. Sustainability. 2020, 12(5), 1755. ISSN 2071-1050. DOI 10.3390/su12051755.

  12. NAVRÁTILOVÁ, Zdeňka - PATOČKA, Jiří. Světlice barvířská (Carthamus tinctorius L.) a její účinky na nervový systém. Psychiatrie. 2020, 24(2), 75-78. ISSN 1211-7579.

  13. NUNHART, Patrik - KONKOLOVA, Eva - JANOVEC, Ladislav - KASPARKOVA, Jana - MALINA, Jaroslav - BRABEC, Viktor - MATEJOVA, Maria - MILTAKOVA, Beata - NOVOTNY, Ladislav - PHILLIPS, Oludotun A - UDO, Edet - KOŽURKOVÁ, Mária. Antimicrobial activity and DNA/HSA interaction of fluorinated 3,6,9-trisubstituted acridines. CHEMICAL PAPERS. 2020, 74(7), 2327-2337. ISSN 2585-7290. DOI 10.1007/s11696-020-01079-4.

  14. PATOČKA, Jiří - NAVRÁTILOVÁ, Zdeňka. Cynomorium plants: bioactive compounds and pharmacologic actions. Military Medical Science Letters - Vojenské zdravotnické listy. 2020, 89(2), 90-98. ISSN 0372-7025. DOI 10.31482/mmsl.2020.001.

  15. PAVELEK, Zbyšek - ANGELUCCI, Francesco - SOUČEK, Ondřej - KREJSEK, Jan - SOBÍŠEK, Lukáš - KLÍMOVÁ, Blanka - ŠARLÁKOVÁ, Jana - HALÚSKOVÁ, Simona - KUČA, Kamil - VALIŠ, Martin. Innate Immune System and Multiple Sclerosis. Granulocyte Numbers Are Reduced in Patients Affected by Relapsing-Remitting Multiple Sclerosis during the Remission Phase. Journal of Clinical Medicine. 2020, 9(5), 1468. ISSN 2077-0383. DOI 10.3390/jcm9051468.

  16. SABOLOVÁ, Danica - KRISTIAN, Pavol - KOŽURKOVÁ, Mária. Proflavine/acriflavine derivatives with versatile biological activities. Journal of Applied Toxicology. 2020, 40(1), 64-71. ISSN 0260-437X. DOI 10.1002/jat.3818.

  17. SALAJKOVÁ, Šárka - BENKOVÁ, Markéta - MAREK, Jan - SLEHA, Radek - PRCHAL, Lukáš - MALIŇÁK, Dávid - DOLEŽAL, Rafael - SEPČIC, Kristina - GUNDE-CIMERMAN, Nina - KUČA, Kamil - SOUKUP, Ondřej. Wide-Antimicrobial spectrum of picolinium salts. Molecules. 2020, 25(9), 2254. ISSN 1420-3049. DOI 10.3390/molecules25092254.

  18. SHARMA, Srishti - SINGH, Namrata - NEPOVIMOVA, Eugenie - KORÁBEČNÝ, Jan - KUCA, Kamil - SATNAMI, Manmohan L - GHOSH, Kallol K. Interaction of synthesized nitrogen enriched graphene quantum dots with novel anti-Alzheimer's drugs: spectroscopic insights. Journal of Biomolecular Structure and Dynamics. 2020, 38(6), 1822-1837. ISSN 0739-1102. DOI 10.1080/07391102.2019.1619625.

  19. SCHMIDT, Monika - BENEK, Ondřej - VINKLÁŘOVÁ, Lucie - HRABINOVÁ, Martina - ZEMANOVA, Lucie - CHRIBEK, Matej - KRALOVA, Vendula - HROCH, Lukáš - DOLEŽAL, Rafael - LYCKA, Antonin - PRCHAL, Lukáš - JUN, Daniel - AITKEN, Laura - GUNN-MOORE, Frank - KUCA, Kamil - MUSÍLEK, Kamil. Benzothiazolyl ureas are low micromolar and uncompetitive inhibitors of 17 beta-HSD10 with implications to Alzheimer's disease treatment. International Journal of Molecular Sciences [online]. 2020, 21(6), 2059. ISSN 1422-0067. DOI 10.3390/ijms21062059.

  20. ŽĎÁROVÁ KARASOVÁ, Jana - SOUKUP, Ondřej - KORÁBEČNÝ, Jan - HROCH, Miloš - KREJCIOVA, Marketa - HRABINOVÁ, Martina - MISÍK, Jan - NOVOTNY, Ladislav - ŠEPSOVÁ, Vendula - KUČA, Kamil. Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats. Drug and Chemical Toxicology. 2020, ISSN 0148-0545. DOI 10.1080/01480545.2019.1566350.

  21. ŽĎÁROVÁ KARASOVÁ, Jana - HEPNAROVÁ, Vendula - ANDRYS, Rudolf - LISA, Miroslav - JOŠT, Petr - MÚČKOVÁ, Ľubica - PEJCHAL, Jaroslav - HERMAN, David - JUN, Daniel - KASSA, Jiri - KUCA, Kamil. Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness. Toxicology Letters. 2020, 320(March), 64-72. ISSN 0378-4274. DOI 10.1016/j.toxlet.2019.11.021.

  22. MARESOVA, Petra - KLIMOVA, Blanka - HONEGR, Jan - KUCA, Kamil - IBRAHIM, Wan Nur Hidayah - SELAMAT, Ali. Medical device development process, and associated risks and legislative aspects-systematic review. Frontiers in Public Health, 2020, 8(July), Art. No. 308. DOI: 10.3389/fpubh.2020.00308. ISSN 2296-2565. 

  23. JOVIC, Danica - JACEVIC, Vesna - KUČA, Kamil - BORISEV, Ivana - MRDJANOVIC, Jasminka - PETROVIC, Danijela - SEKE, Mariana - DJORDJEVIC, Aleksandar. The puzzling potential of carbon nanomaterials: General properties, application, and toxicity. Nanomaterials, 2020, 10(8), Art. No. 1508. DOI: 10.3390/nano10081508. ISSN 2079-4991.

  24. PATOČKA, Jiří - NEPOVÍMOVÁ, Eugenie - WU, Wenda - KUČA, Kamil. Digoxin: Pharmacology and toxicology-A review. Environmental Toxicology and Pharmacology, 2020, 79(October), Art. No. 103400. DOI: 10.1016/j.etap.2020.103400. ISSN 1382-6689.

  25. SOBOLOVÁ, Kateřina - HRABINOVÁ, Martina - HEPNAROVÁ, Vendula - KUČERA, Tomáš - KOBRLOVÁ, Tereza - BENKOVÁ, Markéta - JANOČKOVÁ, Jana - DOLEŽAL, Rafael - PRCHAL, Lukáš - BENEK, Ondřej - MEZEIOVÁ, Eva - JUN, Daniel - SOUKUP, Ondřej - KORÁBEČNÝ, Jan. Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile. European Journal of Medicinal Chemistry, 2020, 203(October), Art. No. 112593. DOI: 10.1016/j.ejmech.2020.112593. ISSN 0223-5234.

  26. MEZEIOVÁ, Eva - SOUKUP, Ondřej - KORÁBEČNÝ, Jan. Huprines - an insight into the synthesis and biological properties. Russian Chemical Reviews, 2020, 89(10), 999-1039. DOI: 10.1070/RCR4938. ISSN 0036-021X.

  27. BENKOVÁ, Markéta - SOUKUP, Ondřej - MAREK, Jan. Antimicrobial susceptibility testing: currently used methods and devices and the near future in clinical practice. Journal of Applied Microbiology, 2020, 129(4), 806-822. ISSN 1364-5072. 

  28. GODYN, Justyna - GUCWA, Dominika - KOBRLOVÁ, Tereza - NOVÁK, Martin - SOUKUP, Ondřej - MALAWSKA, Barbara - BAJDA, Marek. Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability. Talanta, 2020, 217(September), Art. No. 121023. ISSN 0039-9140.

  29. MEZEIOVÁ, Eva - JANOČKOVÁ, Jana - KONEČNÝ, Jan - KOBRLOVÁ, Tereza - PASDIOROVÁ, Markéta - DOLEŽAL, Rafael - PRCHAL, Lukáš - ŽĎÁROVÁ KARASOVÁ, Jana - SOUKUP, Ondřej - KORÁBEČNÝ, Jan. From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia. Bioorganic Chemistry, 2020, 103(October), Art. No. 104179. ISSN 0045-2068.

  30. MONTESDEOCA-ESPONDA, Sarah - ESTHER TORRES-PADRON, Maria - NOVÁK, Martin - KRCHOVÁ, Lucie - SOSA-FERRERA, Zoraida - JUAN SANTANA-RODRIGUEZ, Jose. Occurrence of benzotriazole UV stabilizers in coastal fishes. Journal of Environmental Management, 2020, 269(September), Art. No. 110805. ISSN 0301-4797.

  31. DE CASTRO, Alexandre A. - POLISEL, Daniel A. - PEREIRA, Bruna T. L. - DA CUNHA, Elaine F. F. - KUČA, Kamil - NEPOVIMOVA, Eugenie - RAMALHO, Teodorico C.. Understanding the interaction modes and reactivity of trimedoxime towardMmAChE inhibited by nerve agents: Theoretical and experimental aspects. International Journal of Molecular Sciences [online], 2020, 21(18), Art. No. 6510. ISSN 1422-0067.

  32. SHARMA, Srishti - BANJARE, Manoj Kumar - SINGH, Namrata - KORÁBEČNÝ, Jan - KUČA, Kamil - GHOSH, Kallol K. Multi-spectroscopic monitoring of molecular interactions between an amino acid-functionalized ionic liquid and potential anti-Alzheimer's drugs. RSC Advances, 2020, 10(64), 38873-38883. ISSN 2046-2069. 

  33. SKRENKOVA, Kristyna - SONG, Jae-man - KORTUS, Stepan - KOLCHEVA, Marharyta - NETOLICKY, Jakub - HEMELIKOVA, Katarina - KANIAKOVA, Martina - KRAUSOVA, Barbora Hrcka - KUCERA, Tomas - KORÁBEČNÝ, Jan - SUH, Young Ho - HORAK, Martin. The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors. Scientific Reports, 2020, 10(1), Art. No. 18576. ISSN 2045-2322. 

  34. KUMAR, Harsh - CHEN, Bing-Huei - KUČA, Kamil - NEPOVIMOVA, Eugenie - KAUSHAL, Ankur - NAGRAIK, Rupak - BHATIA, Shashi Kant - DHANJAL, Daljeet Singh - KUMAR, Vinod - KUMAR, Anil - UPADHYAY, Navneet Kumar - VERMA, Rachna - KUMAR, Dinesh. Understanding of Colistin Usage in Food Animals and Available Detection Techniques: A Review. Animals [online], 2020, 10(10), Art. No. 1892. ISSN 2076-2615. 

  35. HYMPÁNOVÁ, Michaela - TERLEP, Sasa - MARKOVÁ, Aneta - PRCHAL, Lukáš - DOGSA, Iztok - PULKRÁBKOVÁ, Lenka - BENKOVÁ, Markéta - MAREK, Jan - STOPAR, David. The antibacterial effects of new N-Alkylpyridinium salts on planktonic and biofilm bacteria. Frontiers in Microbiology, 2020, 11(October), Art. No. 573951. ISSN 1664-302X.

  36. ŽĎÁROVÁ KARASOVÁ, Jana - HROCH, Miloš - POHANKA, Miroslav - HEPNAROVÁ, Vendula - PEJCHAL, Jaroslav - KUČA, Kamil. Pyridostigmine bromide and its relation to Gulf War illness. Toxin Reviews, 2020, 39(2), 138-146. ISSN 1556-9543.

  37. ZEMANOVA, Lucie - VASKOVA, Michaela - SCHMIDT, Monika - ROUBALOVA, Jana - HALECKOVA, Annamaria - BENEK, Ondrej - MUSÍLEK, Kamil. RNase T1 refolding assay for determining mitochondrial cyclophilin D activity: A novel in vitro method applicable in drug research and discovery. Biochemistry, 2020, 59(17), 1680-1687. ISSN 0006-2960.


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